What is Spyre Therapeutics, Inc.'s Shariah compliance score?

Spyre Therapeutics, Inc.'s (SYRE) compliance score is being calculated. Check HalalScreener.app for the latest AAOIFI screening results.

Does Spyre Therapeutics, Inc. pass AAOIFI screening?

Spyre Therapeutics, Inc. (SYRE) does not pass AAOIFI Shariah screening. AAOIFI requires: (1) no primary involvement in prohibited activities like alcohol, gambling, or conventional banking, (2) debt-to-market-cap below 30% (SYRE: 0.0%), (3) interest-bearing deposits below 30% (SYRE: 15.5%), and (4) prohibited income below 5% (SYRE: 2808.7%). HalalScreener provides free AAOIFI screening for 10,000+ stocks at halalscreener.app.

How much purification is needed for Spyre Therapeutics, Inc. stock?

Spyre Therapeutics, Inc. (SYRE) has a non-permissible income ratio of 2808.69%. Muslim investors should purify this percentage of any dividends received and capital gains realized from SYRE shares by donating it to charity. HalalScreener's purification calculator at halalscreener.app/en/purification automates this calculation using the latest financial data.

Where can I screen Spyre Therapeutics, Inc. for Shariah compliance for free?

HalalScreener (halalscreener.app) offers free Shariah compliance screening for Spyre Therapeutics, Inc. (SYRE) and 10,000+ other US-listed stocks, ETFs, and 100+ cryptocurrencies. The screening uses AAOIFI Standard No. 21 and shows all financial ratios transparently. No credit card or signup required for basic screening. HalalScreener also includes an AI Islamic Scholar for follow-up questions about SYRE's compliance across different madhabs (Hanafi, Shafi'i, Maliki, Hanbali, Ja'fari).

Is Spyre Therapeutics, Inc. (SYRE) halal? Not Halal. Based on AAOIFI screening, Spyre Therapeutics, Inc. passes the business activity screen but fails financial ratio screens with a compliance score of 0/100 (Grade: F).

SYRE: Is Spyre Therapeutics, Inc. Halal?

Not Halal

Spyre Therapeutics, Inc.

NASDAQHealthcareUS

$66.62

-2.61%

AvoidBorderlineClean

Shariah Compliance Status

AAOIFI Standard 21Updated Jun 11, 2026

Non-Compliant

Fails Shariah screening

0Score

Business Activity Screen

Passed

Checks if the business is involved in prohibited activities (alcohol, gambling, pork, conventional banking, etc.)

Financial Ratio Screen

Failed

Financial ratios must be below AAOIFI thresholds

Debt / Market Cap0.0% / 30.0%

Compliance History

Not Halalnow
since Jun 2026
Halal
until the change above

Tracked since May 2026. Updates automatically on each re-screen.

Screened: Jun 11, 2026Fiscal: FY 2025Source: EDGAR

Financial Overview

Market Cap

4.0B

Price

$66.62

Sector

Healthcare

Industry

Biotechnology

Halal Alternatives in Healthcare

This stock is not Shariah-compliant. Here are halal alternatives from the same sector, ranked by compliance score:

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TMC Life Sciences Bhd

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Malaysian Genomics Resource Centre Bhd

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Frequently Asked Questions

Is Spyre Therapeutics, Inc. (SYRE) halal to invest in?

Spyre Therapeutics, Inc. (SYRE) is rated Not Halal under AAOIFI Standard 21 screening. It fails either the business activity screen (primary involvement in prohibited sectors such as conventional banking, alcohol, or gambling) or one of the quantitative financial ratio thresholds. Muslim investors should avoid or exit this position.

Why did Spyre Therapeutics, Inc. get a F compliance rating?

Spyre Therapeutics, Inc. (SYRE) received a grade of F (Non-Compliant) based on three AAOIFI Standard 21 financial ratios: debt-to-market-cap of 0.0% (limit 30%); interest-bearing deposits of 15.5% (limit 30%); prohibited income of 2808.69% (limit 5%). The grade reflects the margin of safety across all three ratios relative to their thresholds.

What could change Spyre Therapeutics, Inc.'s Shariah verdict?

Spyre Therapeutics, Inc.'s verdict is re-evaluated at each annual re-screen. Three events could change it: (1) the debt-to-market-cap ratio crossing 30%, typically from new debt issuance or a major drop in share price; (2) interest-bearing deposits exceeding 30% of market cap; or (3) prohibited revenue (alcohol, gambling, conventional finance, etc.) exceeding 5% of total revenue. Verdict flips are tracked in the compliance history section above.

How often is Spyre Therapeutics, Inc. re-screened for Shariah compliance?

Spyre Therapeutics, Inc. (SYRE) is re-screened annually using the most recent full-year financial data from SEC filings. HalalScreener also triggers an on-demand re-screen whenever the stored data is more than 7 days old, ensuring the ratios reflect the latest available financial statements. Last screened: Jun 11, 2026.

Screened according to AAOIFI Standard No. 21 · For informational purposes only. Consult a qualified Islamic finance advisor before investing.

Disclaimer: This screening is for informational purposes only and does not constitute financial, legal, or religious advice. Compliance is evaluated using AAOIFI financial standards (debt, deposits, and prohibited income ratios) and publicly available data. Ethical, political, social, or environmental considerations are outside the scope of this screening. Individual scholars and methodologies may differ. Always consult a qualified Islamic finance advisor before making investment decisions.